In 2021, a 67 – year – old pancreatic cancer patient created a medical miracle. After experiencing surgery, multiple rounds of chemotherapy, and the failure of TIL therapy, the clinical trial of TCR-T cell therapy she participated in made the lung metastases shrink by 72% within 6 months. This breakthrough result was published in the New England Journal of Medicine, bringing new hope to patients with solid tumors worldwide.
The International Consultation Center of Beijing South Suburb Oncology Hospital (400 – 880 – 3716) can build a bridge to international advanced medical care for patients with its rich international resources and plays a crucial role in international consultations and medical treatment.
About TCR-T Therapy
TCR-T cell therapy, the full name of which is T – cell receptor engineered T – cell therapy, is a novel adoptive cell immunotherapy method. Its core principle is to extract T cells from the patient’s body and introduce the TCR gene that can recognize specific tumor antigens into the T cells through genetic engineering technology. As a result, the modified T cells can accurately recognize and bind to the antigens on the surface of tumor cells, thereby activating the immune killing function of T cells and achieving the goal of eliminating tumor cells.
A Success Story of TCR-T Therapy: The Miracle of a Patient with KRAS G12D – Mutated Pancreatic Cancer
Before being diagnosed with pancreatic head adenocarcinoma, this 67 – year – old patient had suffered a great deal due to repeated attacks of pancreatitis and biliary stricture. After the diagnosis, she underwent four cycles of the FOLFIRINOX neoadjuvant chemotherapy regimen, followed by surgical resection and then additional chemotherapy. This enabled her condition to be controlled for a certain period, and the tumor did not progress further.
However, the good times did not last long. In 2019, the patient developed lung metastases, which undoubtedly posed a huge challenge to the treatment. In 2020, she participated in a clinical trial of tumor – infiltrating lymphocyte therapy, but six months later, the lung metastatic lesions progressed again, indicating that the previous treatment methods could no longer effectively control the development of the tumor.
When the patient was almost in despair, in May 2021, the US Food and Drug Administration approved a new drug research application, which became an important turning point in her life – she was introduced to TCR-T cell therapy. In June 2021, she received autologous peripheral blood T – cell treatment. Surprisingly, one month after the cell infusion, the patient’s lung metastatic lesions regressed significantly, and the tumor shrank by 62%. Just half a year later, the tumor had shrunk by 72%.
This remarkable therapeutic effect fully demonstrates the great potential of TCR-T cell therapy in cancer treatment.
For cancer patients, obtaining an accurate diagnosis and the best treatment plan is crucial. However, due to differences in medical levels and technologies in different regions, patients may not be able to obtain the most advanced treatment advice locally. International consultations provide patients with an opportunity to communicate with top international experts, enabling them to learn about the latest treatment methods and research results worldwide.
Through international consultations, patients can receive multi – disciplinary evaluations from experts from different countries and regions. These experts have rich clinical experience and professional knowledge and can analyze and judge the patient’s condition from different perspectives to develop more personalized and precise treatment plans.
In addition, international consultations can also help patients learn about some clinical trials and treatment methods that have not yet been carried out in China, providing them with more treatment options.
The International Department of Beijing South Suburb Oncology Hospital (400 – 880 – 3716) is well aware of the importance of international consultations for cancer patients. Therefore, it actively builds an international medical exchange platform to provide patients with professional and efficient international consultation services. At the International Department of Beijing South Suburb Oncology Hospital, patients can participate in international consultations either online or offline. Our medical team will collect the patient’s medical records, test reports and other information in advance and translate them into English to ensure that international experts can fully understand the patient’s condition. During the consultation, international experts will communicate face – to – face with the patient, ask detailed questions about the patient’s medical history, symptoms, and treatment situation, and then combine the latest medical research results and clinical experience to develop the most suitable treatment plan for the patient.
At the same time, the International Department of Beijing South Suburb Oncology Hospital will also provide patients with full – service translation and coordination services to ensure the smooth progress of the consultation. After the consultation, we will promptly feedback the consultation results and treatment suggestions to the patient and provide follow – up treatment guidance and support.
To enable patients to obtain international experts’ diagnosis and treatment suggestions as soon as possible, the International Department of Beijing South Suburb Oncology Hospital has simplified the consultation service process. Patients only need to call 400 – 880 – 3716 and provide relevant medical records and test reports. The professional team of the International Department of Beijing South Suburb Oncology Hospital will arrange an appropriate international expert for the patient to consult within the shortest time. During the consultation, the professional translation team will ensure smooth and accurate communication between doctors and patients, enabling patients to clearly understand the experts’ opinions and suggestions. In addition, the International Department of Beijing South Suburb Oncology Hospital can also assist patients in handling referral procedures, arranging itineraries, etc., providing one – stop services.
Case Sharing and Inspiration
In addition to the above case of the patient with KRAS G12D – mutated pancreatic cancer, the International Department of Beijing South Suburb Oncology Hospital has also helped foreign cancer patients achieve good treatment results through medical treatment in China.
In June 2024, a non – small cell lung cancer patient from North Korea sought our help. Lung cancer is one of the malignant tumors with the highest incidence rates globally and in China. In 2022, there were about 1.06 million new cases and about 740,000 deaths from lung cancer in China, among which non – small cell lung cancer (NSCLC) accounts for about 80% – 85%.
The patient carried an EGFR mutation and had received treatments such as afatinib and osimertinib. Although she had actively received various treatments, bad news still came in May 2024, and the patient’s condition progressed. So she came to China for our help.
After testing, the patient’s mesothelin (MSLN) expression was 75%. Then we helped the patient find the latest treatment plan across the country. Now the patient’s condition has been alleviated, and the lung nodules have shrunk, as shown in the figure below.
This case tells us that for cancer patients, they should not easily give up the opportunity for treatment. Even if the domestic treatment is in a dilemma, they can also understand the latest international treatment methods and research results through international consultations and strive for more treatment opportunities for themselves.
How to Contact the International Department of Beijing South Suburb Oncology Hospital
If you or your family members are suffering from cancer and hope to learn about international cutting – edge treatment methods or seek international experts’ diagnosis and treatment suggestions, please call the phone number of the International Department of Beijing South Suburb Oncology Hospital (400 – 880 – 3716). The professional team will answer your questions, arrange international consultations for you, and provide you with all – round support and assistance.
Cancer treatment is a long and difficult battle, but we believe that with the continuous progress of medical technology, more and more cancer patients will be able to overcome the disease and regain their health. The International Department of Beijing South Suburb Oncology Hospital will continue to strive to continuously improve its service level and medical capabilities and provide high – quality international medical services for more cancer patients. Let’s work hand in hand to jointly fight against cancer and create miracles of life!
At present, there are still many clinical trials of new anti-cancer technologies in China seeking patients. Consultation on new drugs and technologies, you can contact Beijing South Region Oncology Hospital International Department.
Phone Number：4008803716
Email：myimmnet@163.com
Post time: May-15-2025